Pegram is a surname. Notable people with the surname include:
- George B. Pegram (1876–1958), American physicist
- George H. Pegram (1855–1937), engineer who patented the Pegram truss for bridges
- Henry Alfred Pegram (1862-1937), British sculptor
- John Pegram (1773–1831), Virginia politician
- John Pegram (general) (18i32–1865), Confederate general from Virginia
Places
- For the locality in Idaho see Pegram, Idaho
- For the locality in Tennessee see Pegram, Tennessee
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