Peñalosa or, frequently misspelled, Penalosa may refer to:
People with the surname
- Diego Peñalosa, (1690 - ?) Spanish governor of Cuba
- Gil Penalosa, (born 1956 or 1957) Canadian urbanist and runner-up in the 2022 Toronto mayoral election
- Diosdado "Dodie Boy" Peñalosa (born 1962), retired Filipino boxer and a former IBF champion
- Enrique Peñalosa (born 1954), Colombian politician and former mayor of Bogotá
- Francisco de Peñalosa (1470–1528), Spanish composer of the middle Renaissance
- Gerry Peñalosa, Filipino professional boxer
Places
- Penalosa, Kansas, city in Kingman County, Kansas, United States
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