Phumlani is a South African given name that may refer to
- Phumlani Dlamini (born 1988), Swaziland football defender
- Phumlani Mgobhozi (born 1978), Maskanda artist from South Africa
- Phumlani Nodikida (born 1978), South African rugby union player
- Phumlani Ntshangase (born 1994), South African football midfielder
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