Names | |
---|---|
Other names Polyamine-propyl-biguanidine | |
Identifiers | |
CAS Number | |
Abbreviations | PAPB |
ChemSpider |
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ECHA InfoCard | 100.118.649 |
UNII | |
Properties | |
Chemical formula | (C5H11N5)n |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). N verify (what is ?) Infobox references |
Polyaminopropyl biguanide (PAPB) is a polymer containing biguanide group connected with a three methylene (propyl) linker. The polymer is a propyl analogue of polyhexamethylene biguanide. The polymer display some antibacterial activity however much lower than PHMB. As of May 2024, PAPB is not approved as a biocidal active substance under EU regulations.
Name controversy
In some sources, particularly in lists of cosmetic ingredients (INCI), the name polyaminopropyl biguanide is wrongly associated with polyhexamethylene biguanide (PHMB)
References
- Rembe, J.-D., Fromm-Dornieden, C., Schafer, N., Böhm, J. K., & Stuermer, E. K. (2016). Comparing two polymeric biguanides: chemical distinction, antiseptic efficacy and cytotoxicity of polyaminopropyl biguanide and polyhexamethylene biguanide. *Journal of Medical Microbiology*, 65(8), 867
- European Chemicals Agency (ECHA). (n.d.). List of approved active substances. Retrieved May 24, 2024, from https://echa.europa.eu/regulations/biocidal-products-regulation/approval-of-active-substances/list-of-approved-active-substances
- Cosmetic Ingredient Review Expert Panel (May 12, 2014). "Safety Assessment of Polyaminopropyl Biguanide as Used in Cosmetics" (PDF). Cosmetic Ingredient Review (CIR). Retrieved 2024-05-07.
- Sukakul, Thanisorn; Dahlin, Jakob; Pontén, Ann; Antelmi, Annarita; Bruze, Magnus; Hamnerius, Nils; Hauksson, Inese; Isaksson, Marléne; Lejding, Tina; Svedman, Cecilia (2021). "Contact allergy to polyhexamethylene biguanide (polyaminopropyl biguanide)". Contact Dermatitis. 84 (5): 326–331. doi:10.1111/cod.13728. PMC 8048451. PMID 33098110.