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Polypoid melanoma
Polypoid melanoma of the left ear in 83-year old woman.
Specialty	Dermatology/Oncology

Polypoid melanoma is a rare cutaneous condition, a virulent variant of nodular melanoma. Polypoid melanoma is a subtype of nodular melanoma, the most aggressive form of melanoma (a skin cancer).

Signs and symptoms

Polypoid melanoma is distinguished by a profile that resembles cauliflower and an uneven surface.

Treatment

Therapies for metastatic melanoma include the biological immunotherapy agents ipilimumab, pembrolizumab, and nivolumab; BRAF inhibitors, such as vemurafenib and dabrafenib; and an MEK inhibitor trametinib.

See also

• Melanoma
• List of cutaneous conditions

References

1. James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 978-0-7216-2921-6.
2. Maury, Mikalah E; Jukic, Drazen M (October 13, 2023). "A Case Presentation of Three Polypoid Melanomas With Divergent Features". Cureus. 15 (10). Springer Science and Business Media LLC: e46951. doi:10.7759/cureus.46951. ISSN 2168-8184. PMC 10640706. PMID 38022238.
3. Di Altobrando, Ambra; Patrizi, Annalisa; Dika, Emi; Savoia, Francesco (2020). "Cauliflower-like exophytic mass on the skin: polypoid melanoma. Clinical, dermoscopic, and histologic features". Anais Brasileiros de Dermatologia. 95 (6). Elsevier BV: 748–750. doi:10.1016/j.abd.2020.04.010. ISSN 0365-0596. PMC 7672400. PMID 33041156.
4. Maverakis E, Cornelius LA, Bowen GM, Phan T, Patel FB, Fitzmaurice S, He Y, Burrall B, Duong C, Kloxin AM, Sultani H, Wilken R, Martinez SR, Patel F (2015). "Metastatic melanoma — a review of current and future treatment options". Acta Derm Venereol. 95 (5): 516–524. doi:10.2340/00015555-2035. PMID 25520039.

Further reading

• Hikawa, Renato Shintani; Kanehisa, Eliza Sayuri; Enokihara, Mílvia Maria Simões e Silva; Enokihara, Mauro Yoshiaki; Hirata, Sérgio Henrique (2014). "Polypoid melanoma and superficial spreading melanoma different subtypes in the same lesion". Anais Brasileiros de Dermatologia. 89 (4). FapUNIFESP (SciELO): 666–668. doi:10.1590/abd1806-4841.20142802. ISSN 0365-0596. PMC 4148288. PMID 25054761.
• Manci, Elizabeth A.; Balch, Charles M.; Murad, Tariq M.; Seng/Jaw, Soong (June 1, 1981). "Polypoid Melanoma, A Virulent Variant of the Nodular Growth Pattern". American Journal of Clinical Pathology. 75 (6). Oxford University Press (OUP): 810–815. doi:10.1093/ajcp/75.6.810. ISSN 0002-9173. PMID 7258141.

External links

• Melanoma