Monoclonal antibody | |
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Type | Whole antibody |
Source | Humanized (from mouse) |
Target | beta-amyloid |
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Chemical and physical data | |
Formula | C6552H10158N1730O2090S52 |
Molar mass | 148272.48 g·mol |
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Ponezumab is a humanized monoclonal antibody designed for the treatment of Alzheimer's disease.
Ponezumab was developed by Pfizer Inc. In November 2011 Pfizer halted the development of ponezumab after finishing a phase 2 trial.
References
- "Statement On A Nonproprietary Name Adopted By The USAN Council: Ponezumab" (PDF). American Medical Association.
- Popescu CD, Trofin D, Ignat B, Matei D (2014). "New Aspects of Therapeutic Management in Alzheimer`s Disease". In Atta-ur-Rahman (ed.). Frontiers in Clinical Drug Research: Alzheimer Disorders. Vol. 3. Sharjah: Bentham Science Publishers. p. 55. doi:10.2174/9781681080680115030004. ISBN 978-1-68108-068-0.
- "Alzforum".
Monoclonals for bone, musculoskeletal, circulatory, and neurologic systems | |||||||||
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Angiogenesis inhibitor |
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Growth factor |
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