Press Play may refer to:
- Press Play, a news and culture show hosted by Madeleine Brand on KCRW-FM
- Press Play (band), a Christian pop-rock band
- Press Play (album), a 2006 album by Diddy (Sean Combs)
- Press Play (EP), a 2012 EP by BtoB
- Press Play, a 2006 album by Relâche
- Press Play, a song on Snoop Dogg's 2008 album Ego Trippin'
- Press Play, a 2004 short film starring Jerry Broome
- Press Play, a 2006 short film starring Sam Loggin
- Press Play (film), a 2022 film starring Lewis Pullman and Clara Rugaard
- Press Play (company), a Danish game development studio
See also
- Press to Play, a 1986 album by Paul McCartney
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