Presto chango may refer to:
- "Presto chango", magic words
- Prest-O Change-O, a 1939 Merrie Melodies cartoon
- "Presto Change-O", an episode of The Fairly OddParents (season 5)
- "Presto Change-O", a song by Quasi from the 2006 album When the Going Gets Dark
- Presto Chango, a musical theater/performance group by Jeffrey Morgan
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