Prince Island may refer to:
- Prince Island (California) 34°2′N 120°23′W / 34.033°N 120.383°W / 34.033; -120.383
- Prince Island (Western Australia) 15°13′18″S 128°12′16″E / 15.22167°S 128.20444°E / -15.22167; 128.20444
See also
- Prince Islands, a chain of nine islands off the coast of Istanbul, Turkey
- Prince's Island Park, an urban park in the city of Calgary, Alberta, Canada
- Príncipe, island of the country of São Tomé and Príncipe, once known as Prince's Island
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