Misplaced Pages

Pagodane

Article snapshot taken from Wikipedia with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.
(Redirected from Prinzbach synthesis)

Pagodane
Stereo, skeletal formula of pagodane
Ball and stick model of pagodane
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
PubChem CID
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C20H20/c1-5-13-7-2-8-14(13)6(1)18-10-3-9-15-11-4-12(16(10)15)20(8,18)19(7,11)17(5,9)18/h5-16H,1-4H2Key: HRQVTWFSLAASTF-UHFFFAOYSA-N
SMILES
  • C1C2C3C4CC5C3C1C13C6CC7C8C9CC(C68)C51C49C237
Properties
Chemical formula C20H20
Molar mass 260.380 g·mol
Density 1.629 g/ml
Structure
Point group D2h
Dipole moment 0 D
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references
Chemical compound

Pagodane is an organic compound with formula C
20H
20 whose carbon skeleton was said to resemble a pagoda, hence the name. It is a polycyclic hydrocarbon whose molecule has the D2h point symmetry group. The compound is a highly crystalline solid that melts at 243 °C, is barely soluble in most organic solvents and moderately soluble in benzene and chloroform. It sublimes at low pressure.

The name pagodane is used more generally for any member of a family of compounds whose molecular skeletons have the same 16-carbon central cage as the basic compound. Each member can be seen as the result of connecting eight atoms of this cage in pairs by four alkane chains. The general member is denoted pagodane where m, n, p and q are the number of carbons of those four chains. The general formula is then C
16+sH
12+2s where s= m+n+p+q. In particular, the basic compound C
20H
20 has those carbons connected by four methylene bridges (m=n=p=q=1), and its name within that family is therefore pagodane.

Synthesis and structure

The compound was first synthesized by Horst Prinzbach and his associates in 1987, by a 14-step sequence starting from isodrin. In the process they also synthesized pagodane C
22H
24 and several derivatives.

Prinzbach remarked that "the obvious need for can be readily understood in view of the von Baeyer/IUPAC and Chemical Abstracts nomenclature", undecacycloicosane.

In carbon skeleton of pagodane, there can be distinguished many propellane-type fragments.

The overall synthesis can be summarized as follows:

Synthesis of pagodane starting from isodrin

The scheme depicted here may be shortened to 14 one-pot operations with 24% overall yield. Yet, this variation requires the use of tetrachlorothiophenedioxide instead of tetrachloro-dimethoxycyclopentadiene in two of the early steps. While fewer steps and higher yield look attractive at first sight, this approach had to be given up due to high cost and restricted availability of the dioxide.

Derivatives

Several derivatives are available, such as the diketone C
20H
16O
2 (melting point about 322 °C).

Both pagodane and pagodane form dications in SbF
5/SO
2ClF. In these cations the electron deficiency is spread over the central cyclobutane ring. These dications were the first examples to show the phenomenon of σ-bishomoaromaticity which was subsequently studied by the Prinzbach group to great length.

Pagodane is an isomer of dodecahedrane and can be chemically converted to it.

See also

References

  1. Elegant Solutions: Ten Beautiful Experiments in Chemistry Philip Ball RSC 2005
  2. ^ Wolf-Dieter Fessner, Gottfried Sedelmeier, Paul R. Spurr, Grety Rihs, H. Prinzbach (1987), "Pagodane": the efficient synthesis of a novel, versatile molecular framework. J. Am. Chem. Soc., volume 109 issue 15, pp. 4626–42 doi:10.1021/ja00249a029
  3. H. Prinzbach, F. Wahl, A. Weiler, P. Landenberger, J. Woerth, L.T. Scott, M. Gelmont, D. Olevano, F. Sommer, B. von Issendorff: C20 Carbon Clusters: Fullerene – Boat – Sheet Generation, Mass Selection, PE Characterization. Chem. Eur. J. 2006, 12, 6268-6280 | doi:10.1002/chem.200501611
  4. G. K. Surya Prakash (1998), Investigations on intriguing long lived carbodications. Pure & Appl. Chem., volume 70 issue 10, pp. 2001–06. Online version at iupac.org. Retrieved 2010-01-14. doi:10.1351/pac199870102001
  5. Stable carbocations. Part 267. Pagodane dication, a unique 2.pi.-aromatic cyclobutanoid system G. K. Prakash, V. V. Krishnamurthy, Rainer. Herges, Robert. Bau, Hanna. Yuan, George A. Olah, Wolf Dieter. Fessner, and Horst. Prinzbach Journal of the American Chemical Society 1986 108 (4), 836-838 doi:10.1021/ja00264a046
  6. G.K.S. Prakash, V.V. Krishnamurthy, R. Herges, R. Bau, H. Yuan, G.A Olah, W.-D. Fessner, H. Prinzbach: - and Pagodane Dications: Frozen Two-Electron Woodward-Hoffmann Transition State Models. J. Am. Chem. Soc. 1988, 110, 7764-7772
  7. Wolf-Dieter Fessner, Bulusu A. R. C. Murty, Horst Prinzbach (1987), The Pagodane Route to Dodecahedranes – Thermal, Reductive, and Oxidative Transformations of Pagodanes Angewandte Chemie International Edition in English Volume 26, Issue 5, pp. 451–52 doi:10.1002/anie.198704511
  8. Wolf-Dieter Fessner, Bulusu A. R. C. Murty, Jürgen Wörth, Dieter Hunkler, Hans Fritz, Horst Prinzbach, Wolfgang D. Roth, Paul von Ragué Schleyer, Alan B. McEwen, Wilhelm F. Maier (1987), Dodecahedranes from Pagodanes. Angewandte Chemie International Edition in English, Volume 26, Issue 5, pp. 452–54 doi:10.1002/anie.198704521
Categories: