Prokopchuk is a surname. Notable people with the surname include:
- Yulia Prokopchuk (born 1986), Ukrainian diver
- Ihor Prokopchuk (born 1968), Ukrainian diplomat
- Evgeniy Prokopchuk (born 1994), Russian judoka
- Alexander Prokopchuk (born 1961), Russian police major general, vice-president of Interpol
(born 1994), Russian judoka
- Andriy Prokopchuk (teaches at lcbi)
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