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Propagermanium

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Propagermanium
Names
IUPAC name 3-propanoic acid
Other names proxigermanium, Ge-132, germanium sesquioxide, 2-carboxyethylgermasesquioxane, SK-818, bis(2-carboxyethylgermanium) sesquioxide
Identifiers
CAS Number
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.032.533 Edit this at Wikidata
EC Number
  • 235-800-0
KEGG
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C6H10Ge2O7/c9-5(10)1-3-7(13)15-8(14)4-2-6(11)12/h1-4H2,(H,9,10)(H,11,12)Key: XEABSBMNTNXEJM-UHFFFAOYSA-N
SMILES
  • C(C(=O)O(=O)CCC(=O)O)C(=O)O
Properties
Chemical formula C6H10O7Ge2
Molar mass 339.4222 g/mol
Hazards
GHS labelling:
Pictograms GHS07: Exclamation mark
Signal word Warning
Hazard statements H315, H319, H335
Precautionary statements P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkY verify (what is  ?) Infobox references
Chemical compound

Propagermanium (INN), also known by a variety of other names including bis(2-carboxyethylgermanium) sesquioxide and 2-carboxyethylgermasesquioxane, is an organometallic compound of germanium that is sold as an alternative medicine. It is a polymeric compound with the formula ((HOOCCH2CH2Ge)2O3)n.

The compound was first synthesized in 1967 at the Asai Germanium Research Institute in Japan. It is a water-soluble organogermanium compound used as raw material in nutritional supplements. The compound displays low toxicity in studies with rats.

References

  1. "Bis (2-Carboxyethylgermanium)sesquioxide". pubchem.ncbi.nlm.nih.gov.
  2. M.P. Egorov, P.P. Gaspar (1994), Germanium: Organometallic chemistry in Encyclopedia of Inorganic Chemistry. John Wiley & Sons ISBN 0-471-93620-0
  3. "Asai Germanium Japan". Asai Germanium Japan. Retrieved 2022-02-04.
  4. Doi, Yuko; et al. (2017). "No carcinogenicity of poly-trans-[(2-carboxyethyl) germasesquioxane] (Ge-132): 26-week feeding study using rasH2 mice". Fundamental Toxicological Sciences. 4 (3): 137–150. doi:10.2131/fts.4.137.


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