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Propanediol-phosphate dehydrogenase

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propanediol-phosphate dehydrogenase
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EC no.1.1.1.7
CAS no.9028-15-3
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In enzymology, a propanediol-phosphate dehydrogenase (EC 1.1.1.7) is an enzyme that catalyzes the chemical reaction

propane-1,2-diol 1-phosphate + NAD {\displaystyle \rightleftharpoons } hydroxyacetone phosphate + NADH + H

Thus, the two substrates of this enzyme are propane-1,2-diol 1-phosphate and NAD, whereas its 3 products are hydroxyacetone phosphate, NADH, and H.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is propane-1,2-diol-1-phosphate:NAD oxidoreductase. Other names in common use include PDP dehydrogenase, 1,2-propanediol-1-phosphate:NAD oxidoreductase, and propanediol phosphate dehydrogenase.

References

  • Sellinger OZ, Miller ON (July 1959). "The metabolism of acetol phosphate. II. 1,2-Propanediol-1-phosphate dehydrogenase". The Journal of Biological Chemistry. 234 (7): 1641–6. PMID 13672935.

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Oxidoreductases: alcohol oxidoreductases (EC 1.1)
1.1.1: NAD/NADP acceptor
1.1.2: cytochrome acceptor
1.1.3: oxygen acceptor
1.1.4: disulfide as acceptor
1.1.5: quinone/similar acceptor
1.1.99: other acceptors
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