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In enzymology, a pyridoxamine-phosphate transaminase (EC 2.6.1.54) is an enzyme that catalyzes the chemical reaction

pyridoxamine 5'-phosphate + 2-oxoglutarate ${\displaystyle \rightleftharpoons }$ pyridoxal 5'-phosphate + D-glutamate

Thus, the two substrates of this enzyme are pyridoxamine 5'-phosphate and 2-oxoglutarate, whereas its two products are pyridoxal 5'-phosphate and D-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is pyridoxamine-5'-phosphate:2-oxoglutarate aminotransferase (D-glutamate-forming). Other names in common use include pyridoxamine phosphate aminotransferase, pyridoxamine 5'-phosphate-alpha-ketoglutarate transaminase, and pyridoxamine 5'-phosphate transaminase. This enzyme participates in vitamin B₆ metabolism.

References

• Tani Y, Ukita M, Ogata K (1972). "Studies on vitamin B6 metabolism in microorganisms. Part X. Further purification and characterization of pyridoxamine 5'-phosphate-alpha-ketoglutarate transaminase from Clostridium kainantoi". Agric. Biol. Chem. 36: 181–188. doi:10.1080/00021369.1972.10860239.

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