Quarshie is a surname. Notable people with the surname include:
- Emmanuel Quarshie (1953–2013), Ghanaian footballer
- Ato Quarshie (1944-2019), Ghanaian Politician
- Hugh Quarshie, Ghanaian-born British actor
- Joshua Quarshie (born 2004), German footballer of Ghanaian descent
- Michael Quarshie (born 1979), Finnish American football player of Ghanaian descent
- Tetteh Quarshie (1842–1892), Ghanaian agriculturalist
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