Que Pena Me Da may refer to:
- "Que Pena Me Da", a song by Amarfis
- "Que Pena Me Da", a song by Andy Montañez
- "Que Pena Me Da", a song by Beny Moré
- "Que Pena Me Da", a song by Jesse & Joy from Un Besito Más
- "Que Pena Me Da", a song by Marco Antonio Muñiz
- "Que Pena Me Da", a song by Machito
- "Que Pena Me Da", a song by Oscar D'León
- "Que Pena Me Da", a song by Pandora (band)
- "Que Pena Me Da", a song by Tito Rodríguez
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