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RAB37
Identifiers
Aliases	RAB37, member RAS oncogene family
External IDs	OMIM: 609956; MGI: 1929945; HomoloGene: 23303; GeneCards: RAB37; OMA:RAB37 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) Band 17q25.1 Start 74,670,578 bp End 74,747,335 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 E2 Start 114,982,257 bp End 115,053,062 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cerebellar hemisphere right hemisphere of cerebellum granulocyte monocyte blood nasal epithelium spleen bone marrow cells right lobe of liver endothelial cell Top expressed in islet of Langerhans granulocyte lateral geniculate nucleus anterior horn of spinal cord medial dorsal nucleus medial geniculate nucleus retinal pigment epithelium cerebellar cortex facial motor nucleus lumbar subsegment of spinal cord More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding GTP binding protein binding GTPase activity Cellular component cytoplasmic vesicle endoplasmic reticulum-Golgi intermediate compartment azurophil granule membrane specific granule membrane endosome plasma membrane synaptic vesicle secretory granule membrane intracellular anatomical structure Biological process protein transport neutrophil degranulation vesicle docking involved in exocytosis protein secretion protein localization to plasma membrane regulation of exocytosis intracellular protein transport Rab protein signal transduction small GTPase mediated signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 326624 58222 Ensembl ENSG00000172794 ENSMUSG00000020732 UniProt Q96AX2 Q9JKM7 RefSeq (mRNA) NM_001006637 NM_001006638 NM_001163989 NM_001163990 NM_175738 NM_001330471 NM_001163753 NM_021411 RefSeq (protein) NP_001006639 NP_001157461 NP_001157462 NP_001317400 NP_783865 NP_001157225 NP_067386 Location (UCSC) Chr 17: 74.67 – 74.75 Mb Chr 11: 114.98 – 115.05 Mb PubMed search
Wikidata
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Ras-related protein Rab-37 is a protein that in humans is encoded by the RAB37 gene.

Rab proteins are low molecular mass GTPases that are critical regulators of vesicle trafficking. For additional background information on Rab proteins, see MIM 179508.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000172794 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000020732 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Masuda ES, Luo Y, Young C, Shen M, Rossi AB, Huang BC, Yu S, Bennett MK, Payan DG, Scheller RH (May 2000). "Rab37 is a novel mast cell specific GTPase localized to secretory granules". FEBS Lett. 470 (1): 61–4. doi:10.1016/S0014-5793(00)01288-6. PMID 10722846. S2CID 38218555.
6. ^ "Entrez Gene: RAB37 RAB37, member RAS oncogene family".

Further reading

• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Breuza L, Halbeisen R, Jenö P, et al. (2004). "Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46". J. Biol. Chem. 279 (45): 47242–53. doi:10.1074/jbc.M406644200. PMID 15308636.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801. S2CID 23783563.
• Fukuda M (2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". J. Biol. Chem. 278 (17): 15373–80. doi:10.1074/jbc.M212341200. PMID 12578829.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

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