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RMST (gene)

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RMST
Identifiers
AliasesRMST, LINC00054, NCRMS, NCRNA00054, rhabdomyosarcoma 2 associated transcript (non-protein coding), rhabdomyosarcoma 2 associated transcript
External IDsOMIM: 607045; GeneCards: RMST; OMA:RMST - orthologs
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)
Chromosome 12 (human)Genomic location for RMSTGenomic location for RMST
Band12q23.1|12q21Start97,430,884 bp
End97,598,415 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right lobe of thyroid gland

  • left lobe of thyroid gland

  • anterior pituitary

  • right uterine tube

  • corpus callosum

  • Hypothalamus

  • prostate

  • left uterine tube

  • testicle

  • anterior cingulate cortex
    n/a
More reference expression data
BioGPS
n/a
Orthologs
SpeciesHumanMouse
Entrez

196475

n/a

Ensembl

ENSG00000255794

n/a

UniProt

n
a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)Chr 12: 97.43 – 97.6 Mbn/a
PubMed searchn/a
Wikidata
View/Edit Human

Rhabdomyosarcoma 2 associated transcript (RMST) is a long non-coding RNA. In humans, it is located on chromosome 12q21. It is expressed at higher levels in alveolar rhabdomyosarcoma than in embryonal rhabdomyosarcoma. In the brain, RMST is expressed in the developing ventral midbrain where dopaminergic neurons are formed, the developing isthmus and in the dorsal midline cells of the rostral neural tube. In the midbrain-hindbrain boundary region, its expression is regulated by PAX2.

See also

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000255794 – Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. Chan AS, Thorner PS, Squire JA, Zielenska M (May 2002). "Identification of a novel gene NCRMS on chromosome 12q21 with differential expression between rhabdomyosarcoma subtypes". Oncogene. 21 (19): 3029–3037. doi:10.1038/sj.onc.1205460. PMID 12082533.
  4. Uhde CW, Vives J, Jaeger I, Li M (2010). "Rmst is a novel marker for the mouse ventral mesencephalic floor plate and the anterior dorsal midline cells". PLOS ONE. 5 (1): e8641. Bibcode:2010PLoSO...5.8641U. doi:10.1371/journal.pone.0008641. PMC 2799666. PMID 20062813.
  5. Bouchard M, Grote D, Craven SE, Sun Q, Steinlein P, Busslinger M (June 2005). "Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region". Development. 132 (11): 2633–2643. doi:10.1242/dev.01833. PMID 15872005.

Further reading

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