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Rachel E. Klevit

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American biochemist and academic
Rachel E. Klevit
Alma materReed College, BA, 1978
Oxford University, D.Phil, 1981

Rachel E. Klevit is professor of biochemistry, adjunct professor of chemistry, and adjunct professor of pharmacology at the University of Washington. She holds the Edmond H. Fischer-Washington Research Foundation Endowed Chair in Biochemistry. Klevit's research focuses on molecular interactions in human diseases and includes research on BRCA1, the protein ubiquitination system, and human heat shock proteins.

Education

Klevit received her B.A. in 1978 from Reed College and her D.Phil. from Oxford University in 1981. She completed her post-doctoral training at Duke University Medical Center.

Awards

Klevit was awarded a Rhodes Scholarship in 1978 to attend Oxford University. She received the Margaret Oakley Dayhoff Award in Biophysics from the Biophysical Society in 1987–1988, the Fritz Lippmann Award from the American Society for Biochemistry and Molecular Biology in 2015, and the Dorothy Crowfoot Hodgkin Award from the Protein Society in 2016.

In 2021, she was elected member of the U. S. National Academy of Sciences.

References

  1. Christensen, DE; Brzovic, PS; Klevit, RE (October 2007). "E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages". Nature Structural & Molecular Biology. 14 (10): 941–8. doi:10.1038/nsmb1295. PMID 17873885.
  2. Vittal, V; Wenzel, DM; Brzovic, PS; Klevit, RE (September 2013). "Biochemical and structural characterization of the ubiquitin-conjugating enzyme UBE2W reveals the formation of a noncovalent homodimer". Cell Biochemistry and Biophysics. 67 (1): 103–10. doi:10.1007/s12013-013-9633-5. PMC 3758794. PMID 23709311.
  3. Delbecq, SP; Rosenbaum, JC; Klevit, RE (21 July 2015). "A Mechanism of Subunit Recruitment in Human Small Heat Shock Protein Oligomers". Biochemistry. 54 (28): 4276–84. doi:10.1021/acs.biochem.5b00490. PMC 4512712. PMID 26098708.
  4. "Biochemist Joins National Academy of Sciences". Reed Magazine. Retrieved 2022-03-16.
  5. "The Protein Society Announces Its 2016 Award Recipients" (Press release). Baltimore, MD: The Protein Society. 2016-03-08. Archived from the original on 2016-08-30. Retrieved 2017-03-10.
  6. "News from the National Academy of Sciences". April 26, 2021. Retrieved July 4, 2021. Newly elected members and their affiliations at the time of election are: … Klevit, Rachel; professor, department of biochemistry, University of Washington, Seattle, entry in member directory:"Member Directory". National Academy of Sciences. Retrieved July 4, 2021.

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