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Rachel Wilson is an American professor of neurobiology at Harvard Medical School and is a Howard Hughes Medical Institute Investigator. Wilson's work integrates electrophysiology, calcium imaging, molecular genetics, connectomics, computational modeling, and behavior to explore how neural circuits are organized to sense complex environments, learn associations between environmental features, and organize adaptive behavioral responses.

Education and early career

Wilson was born in Kansas City, Missouri. She received an A.B. in chemistry from Harvard University in 1996 and a Ph.D. in neuroscience from the University of California, San Francisco in 2001, where she worked in the laboratory of Roger Nicoll. There, she searched for the molecule in the brain that enabled neurons to communicate in reverse—known as retrograde signaling—across synapses. She discovered that endocannabinoids—which mimic the active ingredient in marijuana and naturally exist in the brain—were responsible for allowing post-synaptic neurons to communicate to their pre-synaptic counterparts.

Following her Ph.D., Wilson became a postdoctoral researcher at California Institute of Technology, working in the laboratory of Gilles Laurent. There, she began working on Drosophila (fruit flies) as a model organism, seeking to understand how neurons integrate information from their surroundings. She recorded electrical signals in the brain of these flies to understand how those signals corresponded to specific odors as stimuli.

Research

Wilson's laboratory at Harvard University has focused on the neural mechanisms of olfactory and mechanosensory processing, sensory-motor integration, and navigation.

Awards

In 2007 Wilson won Science and Eppendorf AG's Grand Prize in Neurobiology for her work on the olfactory function of fruit flies Drosophila melanogaster, to understand how the brain recognizes odors from patterns of impulses from olfactory receptor neurons.

In 2008 she won a MacArthur Fellowship.

In 2012 she was made a full professor at Harvard Medical School in the Department of Neurobiology; she currently holds the Joseph B. Martin Professorship in Basic Research.

In 2014, she won the inaugural national Blavatnik National Award for Young Scientists, awarded by the Blavatnik Family Foundation and the New York Academy of Sciences to "celebrate America’s most innovative and promising faculty-rank scientists and engineers."

In 2017, Wilson was appointed to the National Academy of Sciences for her contributions to neurophysiology.

References

1. "2008 MacArthur Fellows:Rachel Wilson". MacArthur Foundation. 2008. Archived from the original on 2008-09-27. Retrieved 2008-09-25.
2. ^ "Rachel Wilson: Death Defying". The Scientist Magazine®. Retrieved 2020-03-28.
3. Wilson, Rachel I.; Nicoll, Roger A. (2001-03-29). "Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses". Nature. 410 (6828): 588–592. Bibcode:2001Natur.410..588W. doi:10.1038/35069076. ISSN 1476-4687. PMID 11279497. S2CID 52803281.
4. Carroll, Linda (2002-01-29). "Marijuana's Effects: More Than Munchies". The New York Times. ISSN 0362-4331. Retrieved 2020-03-28.
5. "Young Neurobiologist Honored For Research Into The Fruit-Fly's 'Smell' Circuit". Medical News Today. 2007-10-26.
6. "Mapping the fruit-fly's 'smell' circuit wins Eppendorf/Science Prize:Young neurobiologists honored for research". American Association for the Advancement of Science. 2007-10-25.
7. Carolyn Y. Johnson (2008-09-23). "Local scientists honored, boosted by 'genius' grants: MacArthur fellowships stun winners". Boston Globe.
8. "2014 National Laureates - Blavatnik Awards for Young Scientists". blavatnikawards.org.
9. "Blavatnik Awards for Young Scientists". www.nyas.org.
10. "Rachel Wilson". www.nasonline.org. Retrieved 2019-09-09.

External links

• Wilson Lab at Harvard University

• MacArthur Fellows
• American women neuroscientists
• American neuroscientists
• Harvard College alumni
• University of California, San Francisco alumni
• Harvard Medical School faculty
• Living people
• Scientists from Kansas City, Missouri
• Members of the United States National Academy of Sciences
• American women academics
• 21st-century American women scientists