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Ralph DeBerardinis

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American physician-scientist
Ralph J. DeBerardinis
AwardsPaul Marks Prize for Cancer Research; Edith and Peter O'Donnell Award in Medicine
Scientific career
FieldsCancer; Metabolism
Thesis (1998)
Doctoral advisorHaig H. Kazazian Jr
Other academic advisorsCraig Thompson
Websitehttps://cri.utsw.edu/scientists/ralph-deberardinis-laboratory/

Ralph J. DeBerardinis is an American physician-scientist, the chief of the Division of Pediatric Genetics and Metabolism at the Children’s Medical Center Research Institute at UT Southwestern and a professor at the University of Texas Southwestern Medical Center. DeBerardinis became a Howard Hughes Medical Institute Investigator in 2018. DeBerardinis was elected to the National Academy of Medicine in 2020. DeBerardinis is known for his contributions to research on cancer and pediatric inborn errors of metabolism.

Biography

DeBerardinis was born and raised in the Philadelphia area. DeBerardinis received a Bachelor of Science (BS) degree from St. Joseph’s University and M.D. and Ph.D. degrees from the University of Pennsylvania. DeBerardinis completed his Ph.D. in the laboratory of Haig H. Kazazian Jr. DeBerardinis was an inaugural trainee of the combined Pediatrics/Genetics Residency program at The Children’s Hospital of Philadelphia (CHOP). DeBerardinis has achieved board certifications in clinical biochemical genetics, medical genetics, and pediatrics. DeBerardinis performed his postdoctoral research in the laboratory of Craig Thompson while he was at the Penn Cancer Center. After completing his postdoctoral work, DeBerardinis opened his own research laboratory in 2008 at University of Texas Southwestern Medical Center.

DeBerardinis has been on the Scientific Advisory Boards of several companies, including Agios Pharmaceuticals, Peloton Therapeutics, and Vida Ventures. As of April 2022, DeBerardinis has authored over 350 publications and has an h-index of 94.

Scientific contributions

DeBerardinis is well known for his use of isotope-tracing metabolomics to identify how tumors utilize different nutrients. Using genomics and metabolomics approaches, DeBerardinis also has worked to identify novel mutations that affect the activity of metabolic enzymes.

Selected awards and honors

Selected publications

References

  1. ^ "Ralph J. DeBerardinis". HHMI. Retrieved 2022-04-24.
  2. ^ "National Academy of Medicine Elects 100 New Members". National Academy of Medicine. 2020-10-19. Retrieved 2022-04-24.
  3. ^ "Ralph DeBerardinis - Scientific Advisory Board Member at Vida Ventures". THE ORG. Retrieved 2022-04-24.
  4. ^ "Ralph DeBerardinis Laboratory | Children's Research Institute | Dallas TX". Children's Research Institute | Dallas Texas. Retrieved 2022-04-24.
  5. ^ children's health. "Biography: Ralph John DeBerardinis, MD". Retrieved 2022-04-23.
  6. DeBerardinis, Ralph John (1998). Retrotransposition and evolution of L1 sequences in mammalian genomes (Thesis). OCLC 187477554. ProQuest 304449466.
  7. ^ "Meet Ralph DeBerardinis, a Recipient of the Paul Marks Prize for Cancer Research | Memorial Sloan Kettering Cancer Center". www.mskcc.org. 28 February 2022. Retrieved 2022-04-24.
  8. "Leadership". Agios. Retrieved 2022-04-24.
  9. "Ralph DeBerardinis". scholar.google.com. Retrieved 2022-04-24.
  10. "Ralph DeBerardinis, MD, PhD". HHMI. Retrieved 2022-04-24.
  11. "2017 Outstanding Investigator Award (OIA) Recipients - National Cancer Institute". www.cancer.gov. 2018-10-15. Retrieved 2022-04-24.
  12. "2019 O'Donnell Awards Recipients - TAMEST". TAMEST The Academy of Medicine, Engineering and Science of Texas. Retrieved 2022-04-24.
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