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Redox therapy

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Experimental therapy

Redox therapy is an experimental therapy that aims to effect an outcome by modifying the levels of pro-oxidant and antioxidant agents in cells. The term "redox" is a contraction of "reduction-oxidation". For cancer patients, the therapy is predicated on the idea that the redox state of cells may have an effect on cancer development.

Historically, and in alternative medicine, the term "redox therapy" has also been used to describe the practice of administering high dosages of vitamins; in a 1984 study, high dosages of Menadione and Vitamin C were given to a patient.

See also

References

  1. Douglas Robert Spitz; Kenneth J. Dornfeld; Koyamangalath Krishnan; David Gius (25 November 2011). Oxidative Stress in Cancer Biology and Therapy. Springer. p. 75. ISBN 978-1-61779-397-4. Retrieved 17 August 2013.
  2. Cabello, CM; Bair Wb, 3rd; Wondrak, GT (2007). "Experimental therapeutics: Targeting the redox Achilles heel of cancer". Current Opinion in Investigational Drugs. 8 (12): 1022–37. PMID 18058573.{{cite journal}}: CS1 maint: numeric names: authors list (link)
  3. Ogasawara, Marcia A.; Zhang, Hui (2009). "Redox Regulation and Its Emerging Roles in Stem Cells and Stem-Like Cancer Cells". Antioxidants & Redox Signaling. 11 (5): 1107–1122. doi:10.1089/ars.2008.2308. PMID 18999985.
  4. Chaiswing, Luksana; Zhong, Weixiong; Oberley, Terry D. (2011). "Distinct Redox Profiles of Selected Human Prostate Carcinoma Cell Lines: Implications for Rational Design of Redox Therapy". Cancers. 3 (4): 3557–3584. doi:10.3390/cancers3033557. PMC 3232682. PMID 22163073.
  5. Eleff, S. (1984). "31P NMR Study of Improvement in Oxidative Phosphorylation by Vitamins K3 and C in a Patient with a Defect in Electron Transport at Complex III in Skeletal Muscle". Proceedings of the National Academy of Sciences. 81 (11): 3529–3533. Bibcode:1984PNAS...81.3529E. doi:10.1073/pnas.81.11.3529. PMC 345542. PMID 6587367.
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