ribose 1-dehydrogenase (NADP) | |||||||||
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Identifiers | |||||||||
EC no. | 1.1.1.115 | ||||||||
CAS no. | 37250-46-7 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a ribose 1-dehydrogenase (NADP) (EC 1.1.1.115) is an enzyme that catalyzes the chemical reaction
- D-ribose + NADP + H2O D-ribonate + NADPH + H
The three substrates of this enzyme are D-ribose, NADP, and H2O, whereas its 3 products are D-ribonate, NADPH, and H.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is D-ribose:NADP 1-oxidoreductase. Other names in common use include D-ribose dehydrogenase (NADP), NADP-pentose-dehydrogenase, and ribose 1-dehydrogenase (NADP).
References
- Scher BM, Horecker BL (1966). "Pentose metabolism in Candida. 3. The triphosphopyridine nucleotide-specific polyol dehydrogenase of Candida utilis". Arch. Biochem. Biophys. 116 (1): 117–28. doi:10.1016/0003-9861(66)90020-8. PMID 4381350.
- Schiwara HW, Domschke W, Domagk GF (1968). "". Hoppe-Seyler's Z. Physiol. Chem. 349 (11): 1575–81. doi:10.1515/bchm2.1968.349.2.1575. PMID 4393642.
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