Robert Ayres may refer to:
- Robert M. Ayres (1898–1977), American architect
- Robert Ayres (actor) (1914–1968), American actor
- Robert Ayres (scientist) (1932–2023), American-born scientist
- Bob Ayres (rugby league) (1914–1993), British rugby league player
- Bob Ayres (born 1953), American businessman
See also
- Robert Ayers (born 1985), American football player
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