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Ronidazole

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Not to be confused with ornidazole.
Ronidazole
Names
Preferred IUPAC name (1-Methyl-5-nitro-1H-imidazol-2-yl)methyl carbamate
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.028.796 Edit this at Wikidata
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C6H8N4O4/c1-9-4(3-14-6(7)11)8-2-5(9)10(12)13/h2H,3H2,1H3,(H2,7,11)
SMILES
  • O=C(OCc1ncc(n1C)()=O)N
Properties
Chemical formula C6H8N4O4
Molar mass 200.154 g·mol
Pharmacology
ATCvet code QP51CA02 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references
Chemical compound

Ronidazole is an antiprotozoal agent used in veterinary medicine for the treatment of histomoniasis and swine dysentery as well as Trichomonas gallinae, hexamitosis, Giardia, and Cochlosoma in all aviary birds and pigeons. It may also have use for the treatment of Tritrichomonas foetus infection in cats and for the treatment of Clostridioides difficile infection in humans.

References

  1. Sullivan, T.W.; Grace, O.D.; Aksoy, Ayhan (1977-03-01). "Influence of Level, Timing and Duration of Ronidazole Water Medication on Histomoniasis in Turkeys1". Poultry Science. 56 (2): 571–576. doi:10.3382/ps.0560571. ISSN 0032-5791. PMID 564505.
  2. Olson, L. D.; Rodabaugh, D. E. (July 1976). "Ronidazole in low concentrations in drinking water for treatment and development of immunity to swine dysentery". American Journal of Veterinary Research. 37 (7): 763–767. ISSN 0002-9645. PMID 937800. Archived from the original on 2022-03-17. Retrieved 2022-03-17.
  3. "Ronidazole". All Bird Products. Archived from the original on 2021-05-14. Retrieved 2022-03-17.
  4. Gunn-Moore, Danielle; Lalor, Stephanie (2011-01-01). "Treatment of diarrhoea in cats caused by Tritrichomonas foetus". Veterinary Record. 168 (2): 56–57. doi:10.1136/vr.d189. ISSN 0042-4900. PMID 21257565. S2CID 207041640. Archived from the original on 2022-03-17. Retrieved 2022-03-17.
  5. "Tritrichomonas foetus infection in cats and treatment with RONIDAZOLE" (PDF). University of Edinburgh. December 2009. Archived (PDF) from the original on 2022-03-17. Retrieved 2022-03-17.
  6. Davidson, Gigi S. (December 2006). "Ronidazole in the treatment of trichomonad infections in cats". International Journal of Pharmaceutical Compounding. 10 (6): 434–435. ISSN 1092-4221. PMID 23974416. Archived from the original on 2022-03-17. Retrieved 2022-03-17.
  7. AbdelKhalek, Ahmed; Seleem, Mohamed N. (December 2020). "Repurposing the Veterinary Antiprotozoal Drug Ronidazole for the Treatment of Clostridioides difficile Infection". International Journal of Antimicrobial Agents. 56 (6): 106188. doi:10.1016/j.ijantimicag.2020.106188. ISSN 1872-7913. PMC 7704610. PMID 33045352.
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