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S-Adenosylmethioninamine

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S-Adenosylmethioninamine
Names
IUPAC name S-(3-Aminopropyl)-S-methyl-5′-thioadenosin-5′-ium
Systematic IUPAC name (3-Aminopropyl){methyl}methylsulfanium
Other names S-Adenosyl-(5′)-3-methylthiopropylamine
decarboxylated S-adenosyl methionine
decarboxy-S-adenosyl methionine
(5-Deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium cation
Identifiers
CAS Number
3D model (JSmol)
Abbreviations dAdoMet, dc-SAM
ChEBI
ChemSpider
KEGG
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C14H23N6O3S/c1-24(4-2-3-15)5-8-10(21)11(22)14(23-8)20-7-19-9-12(16)17-6-18-13(9)20/h6-8,10-11,14,21-22H,2-5,15H2,1H3,(H2,16,17,18)/q+1/t8-,10-,11-,14-,24?/m1/s1Key: ZUNBITIXDCPNSD-LSRJEVITSA-N
  • InChI=1/C14H23N6O3S/c1-24(4-2-3-15)5-8-10(21)11(22)14(23-8)20-7-19-9-12(16)17-6-18-13(9)20/h6-8,10-11,14,21-22H,2-5,15H2,1H3,(H2,16,17,18)/q+1/t8-,10-,11-,14-,24?/m1/s1Key: ZUNBITIXDCPNSD-LSRJEVITBK
SMILES
  • C(CCCN)C1(((O1)n2cnc3c2ncnc3N)O)O
Properties
Chemical formula C14H23N6O3S
Molar mass 355.43582 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒N verify (what is  ?) Infobox references
Chemical compound

S-Adenosylmethioninamine is a substrate that is required for the biosynthesis of polyamines including spermidine, spermine, and thermospermine. It is produced by decarboxylation of S-adenosyl methionine.

See also

References

  1. Takahashi, Taku; Kakehi, Jun-Ichi (2009-10-13). "Polyamines: Ubiquitous polycations with unique roles in growth and stress responses". Annals of Botany. 105 (1): 1–6. doi:10.1093/aob/mcp259. PMC 2794062. PMID 19828463.


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