SAPO or Sapo may refer to:
Places
- Sapo National Park, a national park in Sinoe County, Liberia
- Mount Sapo, a mountain in Cochabamba Department, Bolivia
- Mount Sapo, a mountain in Darién Province, Panama
Organisations
- Swedish Security Service (SÄPO)
- SAPO (company) (Serviço de Apontadores Portugueses Online), a Portuguese Internet service provider
- South African Port Operations, the port management subsidiary of Transnet
- South African Post Office, postal service provider in South Africa
- Specialized Anti-Corruption Prosecutor's Office, a Ukrainian governmental agency
Other uses
- SAPO, a silico-alumino-phosphate, a type of zeotype material or molecular sieve, related to zeolites
- SAPO (computer), the first Czechoslovak computer
- Sapo language, a Niger-Congo language of Liberia
- Mount Sapo, fictitious mountain in Italy
- Sapo, Portuguese guitar player for rock band Mão Morta
- sapo, a bar game in South America similar to toad in the hole
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