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SEMA4C

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Protein-coding gene in the species Homo sapiens
SEMA4C
Identifiers
AliasesSEMA4C, M-SEMA-F, SEMACL1, SEMAF, SEMAI, semaphorin 4C
External IDsOMIM: 604462; MGI: 109252; HomoloGene: 23047; GeneCards: SEMA4C; OMA:SEMA4C - orthologs
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)
Chromosome 2 (human)Genomic location for SEMA4CGenomic location for SEMA4C
Band2q11.2Start96,859,718 bp
End96,870,757 bp
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)
Chromosome 1 (mouse)Genomic location for SEMA4CGenomic location for SEMA4C
Band1|1 BStart36,587,720 bp
End36,597,430 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • olfactory bulb

  • trigeminal ganglion

  • spinal ganglia

  • cerebellar vermis

  • tibial nerve

  • inferior ganglion of vagus nerve

  • sural nerve

  • inferior olivary nucleus

  • endothelial cell

  • pericardium
Top expressed in
  • sciatic nerve

  • trigeminal ganglion

  • aortic valve

  • Rostral migratory stream

  • otolith organ

  • utricle

  • ascending aorta

  • ganglionic eminence

  • tail of embryo

  • decidua
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

54910

20353

Ensembl

ENSG00000168758

ENSMUSG00000026121

UniProt

Q9C0C4

Q64151

RefSeq (mRNA)

NM_017789

NM_001126047
NM_001304329
NM_001304330

RefSeq (protein)

NP_060259

NP_001119519
NP_001291258
NP_001291259

Location (UCSC)Chr 2: 96.86 – 96.87 MbChr 1: 36.59 – 36.6 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Semaphorin-4C is a protein that in humans is encoded by the SEMA4C gene.

Interactions

SEMA4C has been shown to interact with DLG4.

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000168758Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000026121Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Inagaki S, Furuyama T, Iwahashi Y (October 1995). "Identification of a member of mouse semaphorin family". FEBS Lett. 370 (3): 269–72. doi:10.1016/0014-5793(95)00850-9. PMID 7656991.
  6. "Entrez Gene: SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C".
  7. Inagaki S, Ohoka Y, Sugimoto H, Fujioka S, Amazaki M, Kurinami H, Miyazaki N, Tohyama M, Furuyama T (March 2001). "Sema4c, a transmembrane semaphorin, interacts with a post-synaptic density protein, PSD-95". J. Biol. Chem. 276 (12): 9174–81. doi:10.1074/jbc.M009051200. PMID 11134026.

Further reading


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