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ST6GALNAC2
Identifiers
Aliases	ST6GALNAC2, SAITL1, SIAT7, SIAT7B, SIATL1, ST6GalNAII, STHM, ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
External IDs	OMIM: 610137; MGI: 107553; HomoloGene: 4714; GeneCards: ST6GALNAC2; OMA:ST6GALNAC2 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) Band 17q25.1 Start 76,565,377 bp End 76,586,956 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 E2 Start 116,566,129 bp End 116,585,694 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tibial nerve right uterine tube right testis left testis sural nerve olfactory zone of nasal mucosa skin of abdomen blood skin of leg testicle Top expressed in seminiferous tubule superior surface of tongue gallbladder corneal stroma right kidney submandibular gland choroid plexus of fourth ventricle crypt of lieberkuhn of small intestine human kidney conjunctival fornix More reference expression data BioGPS More reference expression data
Gene ontology Molecular function glycosyltransferase activity transferase activity sialyltransferase activity alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity Cellular component integral component of membrane Golgi apparatus membrane Golgi membrane Biological process sialylation oligosaccharide metabolic process O-glycan processing protein N-linked glycosylation via asparagine protein glycosylation protein O-linked glycosylation protein sialylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10610 20446 Ensembl ENSG00000070731 ENSMUSG00000057286 UniProt Q9UJ37 P70277 RefSeq (mRNA) NM_006456 NM_009180 RefSeq (protein) NP_006447 NP_033206 Location (UCSC) Chr 17: 76.57 – 76.59 Mb Chr 11: 116.57 – 116.59 Mb PubMed search
Wikidata
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Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 is an enzyme that in humans is encoded by the ST6GALNAC2 gene.

See also

• Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase

References

1. ^ GRCh38: Ensembl release 89: ENSG00000070731 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000057286 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Sotiropoulou G, Kono M, Anisowicz A, Stenman G, Tsuji S, Sager R (May 2002). "Identification and functional characterization of a human GalNAc [alpha]2,6-sialyltransferase with altered expression in breast cancer". Mol Med. 8 (1): 42–55. doi:10.1007/BF03402002. PMC 2039932. PMID 11984005.
6. "Entrez Gene: ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2".

Further reading

• Li GS, Zhu L, Zhang H, et al. (2007). "Variants of the ST6GALNAC2 promoter influence transcriptional activity and contribute to genetic susceptibility to IgA nephropathy". Hum. Mutat. 28 (10): 950–7. doi:10.1002/humu.20543. PMID 17480010. S2CID 7286057.
• Raska M, Moldoveanu Z, Suzuki H, et al. (2007). "Identification and characterization of CMP-NeuAc:GalNAc-IgA1 alpha2,6-sialyltransferase in IgA1-producing cells". J. Mol. Biol. 369 (1): 69–78. doi:10.1016/j.jmb.2007.03.002. PMC 1995659. PMID 17418236.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Samyn-Petit B, Krzewinski-Recchi MA, Steelant WF, et al. (2000). "Molecular cloning and functional expression of human ST6GalNAc II. Molecular expression in various human cultured cells". Biochim. Biophys. Acta. 1474 (2): 201–11. doi:10.1016/s0304-4165(00)00020-9. PMID 10742600.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

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