Sacculus may refer to:
- Saccule, a bed of sensory cells in the inner ear
- Sacculus (insect antenna anatomy), a sensory organ in the antenna of certain insects
- Sacculus (insect genital anatomy), a male genital structure in moths and butterflies
- Sacculus, an outer peptidoglycan meshwork that surrounds the bacterial cytoplasm
- Sacculus, the Latin word for money bag
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