Sampath is a given name and surname. Sampath means prosperity in Hindu/Sanskrit and may also refer to:
- Gaali Sampath, 2021 Indian Telugu-language survival drama film
- Mavinakere Cheluvayyangar (1904–1983), Indian film actor better known by his stage name Sampath
- Mr. Sampath – The Printer of Malgudi, 1949 novel by R. K. Narayan
- Mr. Sampath (1972 film), Indian Tamil-language satirical film
- Onbathu Kuzhi Sampath, 2020 Indian Tamil-language romantic drama film
- Sampath Bank, Sri Lankan commercial bank
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