Sasse or Saße may refer to:
- Sasse Lake, Elysian Township, Le Sueur County, Minnesota
- Student Association at the Stockholm School of Economics
People
- Sasse (musician), Finnish electronic music producer Klas Lindblad
- Angela Sasse, German computer scientist
- Antoinette Sasse (1897–1986), French artist and member of the French Resistance during World War II
- Arthur Sasse (fl. 1951), American photographer most famous for his portrait of Albert Einstein
- Ben Sasse (born 1972), American politician from Nebraska
- Gwendolyn Sasse, British professor of comparative politics
- Hans-Jürgen Sasse (1943–2015), German linguist
- Hermann Sasse (1895–1976), German-Australian Lutheran theologian and author
- Joshua Sasse (born 1987), British actor
- Marie Sasse (1834–1907), Belgian operatic soprano
- Ralph Sasse (1889–1954), college football coach from the United States
- Yan Sasse (born 1997), Brazilian football midfielder
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