Second skin may refer to:
Film and TV
- "Second Skin" (Deep Space Nine), an episode in the TV series Deep Space Nine
- Second Skin (1999 film), a Spanish romantic drama film
- Second Skin (2008 film), a documentary film about Massively Multiplayer Online games (MMOs)
Music
- Second Skin (band), a gothic rock band
Albums
- Second Skin (John Course and mrTimothy album), released in 2008
- Second Skin (The Mayfield Four album), released in 2001
Songs
- Second Skin, a 1982 song by The Chameleons on their debut album Script of the Bridge
- Second Skin, a 1988 song by Hugo Largo on their debut album Drum
- Second Skin (song), released in 1991 by The Gits
- 2econd Skin, a 1998 song by Moonspell on the album Sin/Pecado
- Second Skin, a 2003 song by VNV Nation
Other users
- Second Skin, a 1964 novel by John Hawkes
- Second Skin, a 2008 adventure book based on Doctor Who
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