Seko may refer to:
- Seko language, a language of Sulawesi, Indonesia
- Seko, Indonesia, an area of South Sulawesi, Indonesia
- Seko Rural LLG in Morobe Province, Papua New Guinea
People with the given name
- Seko Fofana (born 1995), Ivorian footballer
- Sekō Higa (比嘉 世幸, 1898–1966), Japanese karateka
People with the surname
- Ayumu Seko (瀬古 歩夢, born 2000), Japanese footballer
- Haruka Seko (born 1996), Japanese BMX rider
- Hiroshi Seko (瀬古浩司), Japanese screenwriter
- Hiroshige Sekō (世耕 弘成, born 1962), Japanese politician
- Mobutu Sese Seko (1930 – 1997), dictator of Zaire from 1965 to 1997
- Toshihiko Seko (瀬古 利彦, born 1956), Japanese long-distance runner
Fiction
- Seko, Khumba's father in Khumba
See also
- Swedish Union for Service and Communications Employees, a trade union in Sweden
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