Sils or SILS may refer to:
Places
- Sils, Girona, a municipality in the comarca of Selva in Catalonia, Spain
- Lake Sils (Catalonia), an ancient lake near Sils, Catalonia, Spain
- Lake Sils, a lake in the Upper Engadine in the Grisons, Switzerland
Other
- Single Incision Laparoscopic Surgery
- UMass SILS, the Summer Institute in Leadership in Sustainability at the University of Massachusetts Amherst
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