Simón de Iriondo (1836–1883) was an Argentine politician of the National Autonomist Party, who was twice governor of the province of Santa Fe, from 1871 to 1874 and from 1878 to 1882.
Iriondo was also the Government Minister of governor Mariano Cabal and part of the cabinet of President Nicolás Avellaneda. After his second term in office, in 1883, he was appointed senator.
As a governor, Iriondo supported the policy of colonization, as Santa Fe was scarcely populated at the time except for the large cities of Santa Fe and Rosario on the banks of the Paraná River. He founded a colony in the north of the province which become the present-day city of Reconquista.
His administration amended the Provincial Constitution of 1863, and created public libraries in Santa Fe, Rosario, San Carlos and Coronda.
| Preceded byMariano Cabal | Governor of Santa Fe 1871–1874 |
Succeeded byServando Bayo |
| Preceded byServando Bayo | Governor of Santa Fe 1878–1882 |
Succeeded byManuel María Zavalla |
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