Simien or Semien may mean:
People
- Wayne Simien, an American professional basketball player
- Terrance Simien, a U.S. zydeco musician, accordionist and songwriter
- Tracy Simien, a former NFL football player
Places
- Kingdom of Simien, a Jewish kingdom said to have been located in the north-western part of Ethiopia
- Simien Mountains, Ethiopia
See also
- Simian, "pertaining to apes"
- Simian (disambiguation)
- Simion, a Romanian name
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