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Pemphigus erythematosus

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(Redirected from Sinear-Usher syndrome) See also: List of target antigens in pemphigus Medical condition
Pemphigus erythematosus
Other namesSenear–Usher syndrome
SpecialtyDermatology Edit this on Wikidata

Pemphigus erythematosus is a localized form of pemphigus foliaceus with features of lupus erythematosus.

Signs and symptoms

Pemphigus erythematosus patients typically present with superficially eroded lesions, or vesiculobullae, that may ooze and crust. This is especially common in areas of the body that are exposed to the sun, like the back, upper chest, and face.

The symptoms of pemphigus erythematosus usually appear slowly and progress slowly. The patient might not even be aware that their pemphigus erythematosus is photosensitive, even though the distribution of the lesions should indicate that they were induced by sunlight.

Causes

Pemphigus patients experience an autoimmune reaction that targets desmosomes. pemphigus erythematosus relapse has been linked to atorvastatin use. There has been one report of a new case of pemphigus erythematosus following topical ingenol mebutate treatment.

Diagnosis

Skin biopsies are used to diagnose pemphigus erythematosus. Immunofluorescence studies are performed on perilesional skin.

Treatment

It has been demonstrated that immunoadsorption and plasmapheresis are useful treatments for pemphigus erythematosus.

See also

References

  1. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
  2. Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). Page 562. McGraw-Hill. ISBN 0-07-138076-0.
  3. ^ Bharti, Rakesh (December 6, 2022). "Pemphigus Erythematosus: Practice Essentials, Etiology, Epidemiology". Medscape Reference. Retrieved February 4, 2024.
  4. Oktarina, Dyah A. M.; Poot, Angelique M.; Kramer, Duco; Diercks, Gilles F. H.; Jonkman, Marcel F.; Pas, Hendri H. (October 1, 2012). "The IgG "Lupus-Band" Deposition Pattern of Pemphigus Erythematosus". Archives of Dermatology. 148 (10). American Medical Association (AMA): 1173–1178. doi:10.1001/archdermatol.2012.1896. ISSN 0003-987X. PMID 22801864.
  5. Lo Schiavo, Ada; Puca, Rosa Valentina; Romano, Francesca; Cozzi, Roberto (2014). "Pemphigus erythematosus relapse associated with atorvastatin intake". Drug Design, Development and Therapy. 8. Informa UK Limited: 1463–1465. doi:10.2147/dddt.s66666. ISSN 1177-8881. PMC 4173814. PMID 25258514.
  6. Kim, YoungJae; Yang, HeeJoo; Lee, WooJin; Won, ChongHyun; Chang, SungEun; Lee, MiWoo; Choi, JeeHo (2021). "A case of new-onset pemphigus erythematosus after topical application of ingenol mebutate". Indian Journal of Dermatology. 66 (5). Medknow: 563. doi:10.4103/ijd.ijd_820_20. ISSN 0019-5154. PMC 8751704. PMID 35068520.
  7. Ogata, Kimiko; Yasuda, Kayo; Matsushita, Mitsuji; Kodama, Hajime (1999). "Successful Treatment of Adolescent Pemphigus Vulgaris by Immunoadsorption Method". The Journal of Dermatology. 26 (4). Wiley: 236–239. doi:10.1111/j.1346-8138.1999.tb03463.x. ISSN 0385-2407. PMID 10343469. S2CID 22757265.
  8. Egan, Conleth A.; Meadows, Kappa P.; Zone, John J. (2000). "Plasmapheresis as a steroid saving procedure in bullous pemphigoid". International Journal of Dermatology. 39 (3). Wiley: 230–235. doi:10.1046/j.1365-4362.2000.00876.x. ISSN 0011-9059. PMID 10759969. S2CID 23582853.

Further reading

External links

ClassificationD
External resources
Vesiculobullous disease
Acantholysis
(epidermis)
Pemphigus
Other
Pemphigoid
(dermis)
IgG:
IgA:
Other bullous
In diseases
classified elsewhere
Categories: