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Si Ni Tang (Chinese: 四逆汤丸) is a brown pill used in Traditional Chinese medicine to "dispel cold and cause restoration upon collapse". It tastes sweet and pungent. It is used upon "collapse with cold sweat, cold limbs, diarrhea with fluid stool containing undigested food, and scarcely perceptible pulse".
The formula (composed of processed Zingiber officinale, Glycyrrhiza uralensis, and Aconitum carmichaelii) has a potential benefit in treating septic shock.
State Pharmacopoeia Commission of the PRC (2005). "Pharmacopoeia of The People's Republic of China (Volume I)". Chemical Industry Press. ISBN7-117-06982-1.
Long Zhixian, Li Qingye, Liu Zhanwen. "Formulas of Traditional Chinese Medicine" (方剂学 fāngjì xué), Academy Press (学苑出版社 xuéyuàn chūbǎnshè), Beijing University of Traditional Medicine. 2005. ISBN7-5077-1270-2.
Chen HC, Chen WC, Lin KH, Chen YH, Lo LC, Lee TC, Hsia TC, Wang CH, Wu SH, Hsu HW, Chang YJ, Huang YC, Ku TH, Horng MH.,"Simultaneous use of traditional Chinese medicine (si-ni-tang) to treat septic shock patients: study protocol for a randomized controlled trial." Trials. 2011;12:199