Sly or SLY may refer to:
People
- Sly Stone (born 1943), American musician in Sly and the Family Stone
- Sylvester Stallone (born 1946), American actor
- Sly Bailey (born 1962), British businesswoman
- Sly Dunbar (born 1952), Jamaican drummer
- Sylvain Grenier (born 1977), Canadian wrestler
- Sly (surname)
Music
- Sly (opera), by Ermanno Wolf-Ferrari
- "Sly" (The Cat Empire song)
- "Sly" (Massive Attack song)
- Sly (band), a Japanese heavy metal band
Gaming
- Sly Cooper (character) in the Sly Cooper series, including:
Other
- sly, ISO 639-3 code for the Selayar language, Indonesia
- Sly syndrome, a genetic disease
- Sly (film), a 2023 documentary film about Sylvester Stallone
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