Smillie is a surname and may refer to:
- Andy Smillie (born 1941), English (soccer) footballer
- Carol Smillie (born 1961), Scottish television presenter, remembered as Wheel of Fortune co-host
- Don Smillie (1910–1993), Canadian ice hockey player
- George Henry Smillie (1840–1921), American landscape painter
- George Frederick Cumming Smillie (1854-1924) United States Engraver
- Grant Smillie (born 1977), Australian music DJ, based in Melbourne
- James Smillie, British and Australian actor, as Dr. Dan Marshall in the Australian soap opera Return to Eden
- James David Smillie (1833–1909), American painter and engraver
- Jennie Smillie Robertson (1878–1981), Canada's first female surgeon
- John Smillie (soccer) (born 1954), retired Scottish-American soccer player
- John Smillie (mathematician) (born 1953), American mathematician
- Neil Smillie (born 1958), English (soccer) football player and manager
- Octavia Hall Smillie (1889–1970), American dietitian
- Raymond Smillie (1904–1993), Canadian boxer who competed in the 1928 Olympics
- Robert Smillie (1857–1940), British trade unionist and Labour Party politician
- Ron Smillie (1933–2005), English footballer
- Ryan Smillie (born 1992), Scottish footballer
- Thomas Smillie (1843 –1917), Scottish-American photographer and archivist with the Smithsonian Institution
- Tuesday Smillie (born 1981), American interdisciplinary artist
- William Smillie (1810–1852), South Australian advocate-general and politician
See also
- Smellie, a surname
- Smelley
- Smiley (disambiguation)
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