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Soft tissue pathology is the subspecialty of surgical pathology which deals with the diagnosis and characterization of neoplastic and non-neoplastic diseases of the soft tissues, such as muscle, adipose tissue, tendons, fascia, and connective tissues. Many malignancies of the soft tissues are challenging for the pathologist to diagnose through gross examination and microscopy alone, and additional tools such as immunohistochemistry, electron microscopy, and molecular pathology techniques are sometimes employed to obtain a definitive diagnosis.

References

1. Kuhn, Karin J.; Cloutier, Jeffrey M.; Boutin, Robert D.; Steffner, Robert; Riley, Geoffrey (2021-01-01). "Soft tissue pathology for the radiologist: a tumor board primer with 2020 WHO classification update". Skeletal Radiology. 50 (1): 29–42. doi:10.1007/s00256-020-03567-w. ISSN 1432-2161.
2. Folpe, Andrew L. (2020-01-01). ""Hey! Whatever happened to hemangiopericytoma and fibrosarcoma?" An update on selected conceptual advances in soft tissue pathology which have occurred over the past 50 years". Human Pathology. 95: 113–136. doi:10.1016/j.humpath.2019.10.001. ISSN 0046-8177.
3. Folpe, Andrew L. (January 2022). "'I Can't Keep Up!': an update on advances in soft tissue pathology occurring after the publication of the 2020 World Health Organization classification of soft tissue and bone tumours". Histopathology. 80 (1): 54–75. doi:10.1111/his.14460. ISSN 1365-2559. PMID 34958510.

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