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SLC9A4
Identifiers
Aliases	SLC9A4, NHE4, solute carrier family 9 member A4
External IDs	OMIM: 600531; MGI: 105074; HomoloGene: 72232; GeneCards: SLC9A4; OMA:SLC9A4 - orthologs
Gene location (Human) Chr. Chromosome 2 (human) Band 2q12.1 Start 102,473,226 bp End 102,533,972 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1 B|1 19.51 cM Start 40,619,241 bp End 40,669,885 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle stomach body of stomach human kidney fundus gallbladder duodenum gastric mucosa olfactory zone of nasal mucosa tonsil Top expressed in stomach dentate gyrus of hippocampal formation granule cell secondary oocyte zygote duodenum primary oocyte hippocampus proper urinary bladder olfactory bulb mammary gland More reference expression data BioGPS n/a
Gene ontology Molecular function solute:proton antiporter activity antiporter activity sodium:proton antiporter activity potassium:proton antiporter activity Cellular component integral component of membrane basolateral plasma membrane apical plasma membrane membrane plasma membrane Biological process gastric acid secretion proton transmembrane transport epithelial cell development cation transport ion transport regulation of pH sodium ion transport regulation of intracellular pH sodium ion import across plasma membrane potassium ion transmembrane transport transmembrane transport anion transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 389015 110895 Ensembl ENSG00000180251 ENSMUSG00000026065 UniProt Q6AI14 Q8BUE1 RefSeq (mRNA) NM_001011552 NM_177084 RefSeq (protein) NP_001011552 NP_796058 Location (UCSC) Chr 2: 102.47 – 102.53 Mb Chr 1: 40.62 – 40.67 Mb PubMed search
Wikidata
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Solute carrier family 9 member A4 is a protein that in humans is encoded by the SLC9A4 gene.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000180251 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000026065 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Solute carrier family 9 member A4". Retrieved 2016-10-26.

Further reading

• Beltrán AR, Ramírez MA, Carraro-Lacroix LR, Hiraki Y, Rebouças NA, Malnic G (2008). "NHE1, NHE2, and NHE4 contribute to regulation of cell pH in T84 colon cancer cells". Pflügers Arch. 455 (5): 799–810. doi:10.1007/s00424-007-0333-0. PMID 17943310. S2CID 21303274.

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