Speakes is an English surname. It may refer to:
People
- Larry Speakes (1939–2014), an acting press spokesman for the White House under President Reagan
- Stephen M. Speakes (b. 1952), a United States Army lieutenant general
Fictional characters
- The Speakeses, a family in the soap opera Guiding Light, including Hampton (Vince Williams), Kathryn (Nia Long) and Gilly Speakes (Amelia Marshall).
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