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Stomoxyn | |||||||||
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Identifiers | |||||||||
Symbol | Stomoxyn | ||||||||
Pfam | PF11585 | ||||||||
InterPro | IPR021037 | ||||||||
OPM superfamily | 151 | ||||||||
OPM protein | 1zrv | ||||||||
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Stomoxyn is an insect antimicrobial peptide localised in the gut epithelium, which functions in killing a range of microorganisms, parasites and some viruses. In water, stomoxyn has a flexible random coil in structure, while in trifluoroethanol it adopts a stable helical structure. Structural similarities to the antimicrobial peptide cecropin A from Hyalophora cecropia suggest that it may function in a similar manner by disrupting the bacterial membrane.
References
- Landon C, Meudal H, Boulanger N, Bulet P, Vovelle F (February 2006). "Solution structures of stomoxyn and spinigerin, two insect antimicrobial peptides with an alpha-helical conformation". Biopolymers. 81 (2): 92–103. doi:10.1002/bip.20370. PMID 16170803. S2CID 24098919.
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