Streptogrisin B

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Streptogrisin B (EC 3.4.21.81, Streptomyces griseus protease B, pronase B, serine proteinase B, Streptomyces griseus proteinase B, Streptomyces griseus proteinase 1, Streptomyces griseus serine proteinase B) is an enzyme. This enzyme catalyses the following chemical reaction

Hydrolysis of proteins with trypsin-like specificity

This enzyme is isolated from Streptomyces griseus.

References

Jurasek L, Fackre D, Smillie LB (September 1969). "Remarkable homology about the disulfide bridges of a trypsin-like enzyme from Streptomyces griseus". Biochemical and Biophysical Research Communications. 37 (1): 99–105. doi:10.1016/0006-291x(69)90885-7. PMID 4899581.
Fujinaga M, Read RJ, Sielecki A, Ardelt W, Laskowski M, James MN (August 1982). "Refined crystal structure of the molecular complex of Streptomyces griseus protease B, a serine protease, with the third domain of the ovomucoid inhibitor from turkey". Proceedings of the National Academy of Sciences of the United States of America. 79 (16): 4868–72. doi:10.1073/pnas.79.16.4868. PMC 346786. PMID 6750612.
Read RJ, Fujinaga M, Sielecki AR, James MN (September 1983). "Structure of the complex of Streptomyces griseus protease B and the third domain of the turkey ovomucoid inhibitor at 1.8-A resolution". Biochemistry. 22 (19): 4420–33. doi:10.1021/bi00288a012. PMID 6414511.
Henderson G, Krygsman P, Liu CJ, Davey CC, Malek LT (August 1987). "Characterization and structure of genes for proteases A and B from Streptomyces griseus". Journal of Bacteriology. 169 (8): 3778–84. doi:10.1128/jb.169.8.3778-3784.1987. PMC 212465. PMID 3112129.
Greenblatt HM, Ryan CA, James MN (January 1989). "Structure of the complex of Streptomyces griseus proteinase B and polypeptide chymotrypsin inhibitor-1 from Russet Burbank potato tubers at 2.1 A resolution". Journal of Molecular Biology. 205 (1): 201–28. doi:10.1016/0022-2836(89)90376-8. PMID 2494344.

External links

Streptogrisin+B at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

v t e Endopeptidases: serine proteases/serine endopeptidases (EC 3.4.21)
Digestive enzymes	Enteropeptidase Trypsin Chymotrypsin Elastase Neutrophil Pancreatic
Coagulation	factors: Thrombin Factor VIIa Factor IXa Factor Xa Factor XIa Factor XIIa Kallikrein PSA KLK1 KLK2 KLK3 KLK4 KLK5 KLK6 KLK7 KLK8 KLK9 KLK10 KLK11 KLK12 KLK13 KLK14 KLK15 fibrinolysis: Plasmin Plasminogen activator Tissue plasminogen activator Urinary plasminogen activator
Complement system	Factor B Factor D Factor I MASP MASP1 MASP2 C3-convertase
Other immune system	Chymase Granzyme Tryptase Proteinase 3/Myeloblastin
Venombin	Ancrod Batroxobin
Other	Acrosin Prolyl endopeptidase Pronase Proprotein convertases 1 2 Prostasin Reelin Subtilisin/Furin/S1P4 Sedolisin/TPP1 Streptokinase Cathepsin A G

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)

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Biology

Category:

EC 3.4.21