Sulfathiourea - Misplaced Pages

Chemical compound Pharmaceutical compound

Sulfathiourea
Clinical data

Other names	(4-aminophenyl)sulfonylthiourea
ATC code	J01EB08 (WHO)
Identifiers
IUPAC name 4-amino-N-(aminocarbonothioyl)benzenesulfonamide
CAS Number	515-49-1
PubChem CID	3000579
ChemSpider	2272143
UNII	MXF9G4I1V5
KEGG	D07239
ChEBI	CHEBI:131723
CompTox Dashboard (EPA)	DTXSID4046868
ECHA InfoCard	100.007.457
Chemical and physical data
Formula	C₇H₉N₃O₂S₂
Molar mass	231.29 g·mol
3D model (JSmol)	Interactive image
SMILES O=S(=O)(c1ccc(N)cc1)NC(=S)N
InChI InChI=1S/C7H9N3O2S2/c8-5-1-3-6(4-2-5)14(11,12)10-7(9)13/h1-4H,8H2,(H3,9,10,13) Key:UEMLYRZWLVXWRU-UHFFFAOYSA-N
(verify)

Sulfathiourea is a sulfonamide antibacterial.

References

Schoog M (November 1953). "". Zeitschrift für Haut- und Geschlechtskrankheiten (in German). 15 (10): 315–8. PMID 13137202.

Antifolates
(inhibit bacterial
purine metabolism,
thereby inhibiting
DNA and RNA
synthesis)

Short-acting	Sulfaisodimidine Sulfamethizole Sulfadimidine Sulfapyridine (Sulfasalazine) Sulfafurazole (Acetyl sulfisoxazole) Sulfanilamide Prontosil Sulfathiazole (Phthalylsulfathiazole, Succinylsulfathiazole) Sulfathiourea
Intermediate-acting	Sulfamethoxazole Sulfadiazine Sulfamoxole
Long-acting	Sulfadimethoxine Sulfadoxine Sulfalene Sulfametomidine Sulfametoxydiazine Sulfamethoxypyridazine Sulfaperin Sulfamerazine Sulfaphenazole Sulfamazone
Other/ungrouped	Mafenide Sulfacetamide Sulfaclozine Sulfadicramide Sulfaguanidine Sulfametrole Sulfanitran

Combinations

Other DHPS inhibitors

Quinolones
(inhibit bacterial
topoisomerase
and/or DNA gyrase,
thereby inhibiting
DNA replication)

2nd generation	Ciprofloxacin Ofloxacin Enoxacin Fleroxacin Lomefloxacin Nadifloxacin/Levonadifloxacin/Alalevonadifloxacin Norfloxacin Pefloxacin Rufloxacin
3rd generation	Levofloxacin Balofloxacin Grepafloxacin Pazufloxacin Sparfloxacin Temafloxacin Tosufloxacin
4th generation	Besifloxacin Delafloxacin Gatifloxacin Finafloxacin Gemifloxacin Moxifloxacin Clinafloxacin Garenoxacin Prulifloxacin Sitafloxacin Trovafloxacin/Alatrofloxacin
Veterinary	Danofloxacin Difloxacin Enrofloxacin Ibafloxacin Marbofloxacin Orbifloxacin Pradofloxacin Sarafloxacin

Newer non-fluorinated

Related (DG)

Nitroimidazole derivatives	Secnidazole

RNA synthesis

Rifamycins/ RNA polymerase	Rifampicin Rifabutin Rifapentine Rifaximin Rifalazil
Lipiarmycins	Fidaxomicin

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