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TAGLN2

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Protein-coding gene in the species Homo sapiens
TAGLN2
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

1WYM

Identifiers
AliasesTAGLN2, HA1756, transgelin 2
External IDsOMIM: 604634; MGI: 1312985; HomoloGene: 20789; GeneCards: TAGLN2; OMA:TAGLN2 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)
Chromosome 1 (human)Genomic location for TAGLN2Genomic location for TAGLN2
Band1q23.2Start159,918,107 bp
End159,925,507 bp
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)
Chromosome 1 (mouse)Genomic location for TAGLN2Genomic location for TAGLN2
Band1 H3|1 79.89 cMStart172,327,614 bp
End172,334,947 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • upper lobe of left lung

  • right lung

  • monocyte

  • granulocyte

  • islet of Langerhans

  • ventricular zone

  • skin of abdomen

  • mucosa of transverse colon

  • minor salivary glands

  • gallbladder
Top expressed in
  • pyloric antrum

  • epithelium of stomach

  • mucous cell of stomach

  • lip

  • tail of embryo

  • right lung

  • yolk sac

  • right lung lobe

  • esophagus

  • left lung
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

8407

21346

Ensembl

ENSG00000158710

ENSMUSG00000026547

UniProt

P37802

Q9WVA4

RefSeq (mRNA)

NM_003564
NM_001277223
NM_001277224

NM_178598

RefSeq (protein)

NP_001264152
NP_001264153
NP_003555

NP_848713

Location (UCSC)Chr 1: 159.92 – 159.93 MbChr 1: 172.33 – 172.33 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Transgelin-2 is a protein that in humans is encoded by the TAGLN2 gene.

The protein encoded by this gene is a homolog of the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The function of this protein has not yet been determined.

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000158710Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000026547Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Stanier P, Abu-Hayyeh S, Murdoch JN, Eddleston J, Copp AJ (Sep 1998). "Paralogous sm22alpha (Tagln) genes map to mouse chromosomes 1 and 9: further evidence for a paralogous relationship". Genomics. 51 (1): 144–7. doi:10.1006/geno.1998.5381. PMID 9693045.
  6. ^ "Entrez Gene: TAGLN2 transgelin 2".

Further reading

PDB gallery
  • 1wym: Solution structure of the CH domain of human transgelin-2 1wym: Solution structure of the CH domain of human transgelin-2


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