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TBC1D9
Identifiers
Aliases	TBC1D9, MDR1, GRAMD9, TBC1 domain family member 9
External IDs	OMIM: 618035; MGI: 1918560; HomoloGene: 57079; GeneCards: TBC1D9; OMA:TBC1D9 - orthologs
Gene location (Human) Chr. Chromosome 4 (human) Band 4q31.21 Start 140,620,782 bp End 140,756,385 bp
Gene location (Mouse) Chr. Chromosome 8 (mouse) Band 8|8 C2 Start 83,891,981 bp End 83,999,563 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in lactiferous duct Epithelium of choroid plexus palpebral conjunctiva lateral nuclear group of thalamus seminal vesicula visceral pleura spinal ganglia parietal pleura Pons trigeminal ganglion Top expressed in Epithelium of choroid plexus trigeminal ganglion superior cervical ganglion cerebellar cortex ventral tegmental area lobe of cerebellum visual cortex transitional epithelium of urinary bladder primary visual cortex pontine nuclei More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding calcium ion binding GTPase activator activity Cellular component endomembrane system intracellular anatomical structure Biological process activation of GTPase activity regulation of vesicle fusion intracellular protein transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23158 71310 Ensembl ENSG00000109436 ENSMUSG00000031709 UniProt Q6ZT07 Q3UYK3 RefSeq (mRNA) NM_015130 NM_001111304 NM_027758 RefSeq (protein) NP_055945 NP_001104774 NP_082034 Location (UCSC) Chr 4: 140.62 – 140.76 Mb Chr 8: 83.89 – 84 Mb PubMed search
Wikidata
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TBC1 domain family member 9 is a protein that in humans is encoded by the TBC1D9 gene.

It is also known as MDR1, GRAMD9.

It is predicted to enable GTPase activator activity. It is also predicted to be involved in activation of GTPase activity and intracellular protein transport.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000109436 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000031709 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Islam TC, Asplund AC, Lindvall JM, Nygren L, Liden J, Kimby E, Christensson B, Smith CI, Sander B (Sep 2003). "High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma". Leukemia. 17 (9): 1880–1890. doi:10.1038/sj.leu.2403057. PMID 12970790.
6. "Entrez Gene: TBC1D9 TBC1 domain family, member 9 (with GRAM domain)".
7. "TBC1D9 TBC1 domain family member 9 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2023-11-28.

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–113. doi:10.1006/abio.1996.0138. PMID 8619474.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (6): 355–364. doi:10.1093/dnares/5.6.355. PMID 10048485.
• Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–3496. Bibcode:2000PNAS...97.3491D. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–716. doi:10.1038/nbt971. PMID 15146197. S2CID 27764390.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–12135. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Rodríguez Nóvoa S, Barreiro P, Rendón A, et al. (2006). "Plasma levels of atazanavir and the risk of hyperbilirubinemia are predicted by the 3435C-->T polymorphism at the multidrug resistance gene 1". Clin. Infect. Dis. 42 (2): 291–295. doi:10.1086/499056. PMID 16355344.

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