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TCP11
Identifiers
Aliases	TCP11, D6S230E, FPPR, t-complex 11
External IDs	OMIM: 186982; MGI: 98544; HomoloGene: 8433; GeneCards: TCP11; OMA:TCP11 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) Band 6p21.31 Start 35,118,071 bp End 35,148,610 bp
Gene location (Mouse) Chr. Chromosome 17 (mouse) Band 17 A3.3|17 14.62 cM Start 28,066,745 bp End 28,080,639 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm left testis right testis testicle gonad oocyte secondary oocyte right uterine tube olfactory zone of nasal mucosa amniotic fluid Top expressed in seminiferous tubule spermatid spermatocyte lens epithelium of lens neural layer of retina motor neuron molar embryo embryo More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component integral component of membrane membrane acrosomal vesicle cytoplasmic vesicle sperm flagellum cell projection sperm midpiece motile cilium cilium Biological process cell differentiation spermatogenesis multicellular organism development protein kinase A signaling regulation of cAMP-mediated signaling regulation of sperm capacitation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6954 21463 Ensembl ENSG00000124678 ENSMUSG00000062859 UniProt Q8WWU5 Q01755 RefSeq (mRNA) NM_001093728 NM_001261817 NM_001261818 NM_001261819 NM_001261820 NM_001261821 NM_018679 NM_001085555 NM_013687 NM_001357681 NM_001374620 NM_001374621 RefSeq (protein) NP_001248746 NP_001248747 NP_001248748 NP_001248749 NP_001248750 NP_061149 NP_001353252 NP_001353253 NP_001353254 NP_001353255 NP_001353256 NP_001353257 NP_001353258 NP_001353259 NP_001353260 NP_001353261 NP_001357616 n/a Location (UCSC) Chr 6: 35.12 – 35.15 Mb Chr 17: 28.07 – 28.08 Mb PubMed search
Wikidata
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T-complex protein 11 homolog is a protein that in humans is encoded by the TCP11 gene.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000124678 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000062859 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Ragoussis J, Senger G, Mockridge I, Sanseau P, Ruddy S, Dudley K, Sheer D, Trowsdale J (Nov 1992). "A testis-expressed Zn finger gene (ZNF76) in human 6p21.3 centromeric to the MHC is closely linked to the human homolog of the t-complex gene tcp-11". Genomics. 14 (3): 673–9. doi:10.1016/S0888-7543(05)80167-3. PMID 1427894.
6. Ma Y, Zhang S, Xia Q, Zhang G, Huang X, Huang M, Xiao C, Pan A, Sun Y, Lebo R, Milunsky A (Jan 2002). "Molecular characterization of the TCP11 gene which is the human homologue of the mouse gene encoding the receptor of fertilization promoting peptide". Molecular Human Reproduction. 8 (1): 24–31. doi:10.1093/molehr/8.1.24. PMID 11756566.
7. "Entrez Gene: TCP11 t-complex 11 (mouse)".

Further reading

• Ma YX, Zhang SZ, Wu QQ, Sun Y, Qiu WM, Xu WM (Apr 2003). "". Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae. 25 (2): 122–8. PMID 12905703.
• Ma YX, Zhang SZ, Wu QQ, Sun Y (Feb 2003). "". Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao Acta Biochimica et Biophysica Sinica. 35 (2): 182–8. PMID 12545228.
• Fraser LR, Hosseini R, Hanyalogou A, Talmor A, Dudley RK (Nov 1997). "TCP-11, the product of a mouse t-complex gene, plays a role in stimulation of capacitation and inhibition of the spontaneous acrosome reaction". Molecular Reproduction and Development. 48 (3): 375–82. doi:10.1002/(SICI)1098-2795(199711)48:3<375::AID-MRD11>3.0.CO;2-V. PMID 9322250. S2CID 42009443.
• Mazarakis ND, Nelki D, Lyon MF, Ruddy S, Evans EP, Freemont P, Dudley K (Feb 1991). "Isolation and characterisation of a testis-expressed developmentally regulated gene from the distal inversion of the mouse t-complex". Development. 111 (2): 561–71. doi:10.1242/dev.111.2.561. PMID 1893875.

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